Hodgkin's disease in patients with previous infectious mononucleosis.

Hematopoietic and lymphatic cancers in relatives of patients with infectious mononucleosis.

BACKGROUND Young adults with a history of Epstein-Barr virus (EBV)-related infectious mononucleosis have an increased risk for Hodgkin's lymphoma. EBV is detected in Hodgkin's lymphoma Reed-Sternberg cells from some patients, but in young adult patients, it is detected at a relatively low frequency in these cells. Hodgkin's lymphoma and infectious mononucleosis are both associated with high soc...

Evaluation of IL-17 and IL-10 Production in Infectious Mononucleosis in EBV Patients

Epstein–Barr virus is primarily the cause of acute infectious mononucleosis and can also cause lymphoma and autoimmune diseases. Th17 cells, which are a unique subset of ThCD4+ cells, direct the infection toward inflammation through production of inflammatory cytokine IL-17. In contrast, Treg Foxp3 cells inhibit inflammation through secretion of anti-inflammatory cytokine IL-10, leading to chro...

Expression of Epstein-Barr virus in Hodgkin lymphoma Specimens in IRAN.

Background & Objectives: The Epstein-Barr Virus (EBV( is related with various diseases including infectious mononucleosis, Burkitt's lymphoma, Hodgkin's lymphoma, nasopharyngeal carcinoma and post-transplant lymphoprolifrative disorders. The aim of this study was to characterize the association between EBV and Hodgkin's lymphoma through EBERs in situ hybridization (EBER-ISH) in Iranian pat...

Hodgkin's disease following infectious mononucleosis.

Survey of the eventual diagnosis in 600 cases referred for a second histological opinion after an initial biopsy diagnosis of Hodgkin's disease.

In a series of 600 cases of lymphadenopathy in which an initial histological diagnosis of Hodgkin's disease was reviewed in a reference laboratory this interpretation was confirmed in 317 cases (53%). In the 283 other cases the diagnosis of Hodgkin's disease was considered to be mistaken. The condition most frequently confused with Hodgkin's disease was chronic non-specific lymphadenitis. Retic...